Department of Anesthesiology & Perioperative Care: School of Medicine: University of California, Irvine
Research

Clinical Research


Research activity in the Department of Anesthesiology & Perioperative Care surged upward in the last two years. Faculty have made significant accomplishments in both clinical and translational research. Indeed the Department is now ranked 26th in the country among anesthesia department for NIH funding, up from 44th.



Lead ResearcherProtocol Title
Lin, M.D.The application of pharmacodynamic and response surface models to improvements in emergence from anesthesia, using the Navigator.

Synopsis: To determine whether the presence of the Navigator® display will shorten the duration of emergence/recovery from general anesthesia.

Hata, MDEfficacy and Feasibility of Ultrasound Guided Sacroiliac Joint Injections

Synopsis: To investigate the efficacy and feasibility of ultrasound guidance during sacroiliac joint injections for the treatment of sacroiliitis.

Rinehart, MDContinuous and Non-Invasive Hemoglobin Identifies Anemia and Prevents Over-Transfusion in Surgical Patients

Synopsis: To determine the accuracy of continuous non-invasive hemoglobin measurements in cancer patients and to determine patient and device variability from multiple measures obtained at the same time with different devices on different fingers and different subjects.

Rinehart, MDNon-invasive Physiological Measurements via Pulse CO-OximetrySynopsis

Synopsis: To assess the accuracy and precision of noninvasive CO-Oximeter monitors in patients with various co-morbidities and extremes of physiology.

Rinehart, MDDesire for information in Adult Patients in the Perioperative Setting

Synopsis: To examine the differences in the desire for information in the perioperative period between different subsets of adults, specifically looking at differences between geriatric patients and younger adults. Geriatric patients are often faced with limitations that younger adult patients do not have and could be considered an at-risk patient population. As such, the geriatric patient population may not be as assertive in the pursuit of desired information as younger patients despite an equitable desire to understand the risks and benefits any proposed procedure. Likewise, generational differences may exist in the overall desire for information about planned interventions. Before specific interventions for improvement can be studied a clearer understanding of the desire for information across different age groups must be examined.

Rinehart, MDResident Evaluation Based on Behavioral Characteristics

Synopsis: Defining specific behaviors present in successful residents in order to use those behaviors to predict which applicants to residency programs will be successful.

Rosenbaum, MDEvaluation of the Accuracy and Precision of the Masimo Labs Pulse-Hemoglobin-Meter Monitor in Surgical Patients

Synopsis: To assess the accuracy and precision of the Masimo Labs pulse hemoglobin noninvasive monitor.

Rosenbaum, MDBio-Acoustical Respiratory Rate Monitoring among Patients in the OR, Post-Operative and General Floor Care Settings

Synopsis: To capture high resolution waveform data and numerical data from the three respiratory rate methods and compare respiratory rate derived from ETCO2 to respiratory rate measured by the Masimo Acoustical Respiratory Rate Monitor. Further, we will determine the number and duration of data drop outs and alarms obtained with each method of respiratory rate monitoring.

Cannesson, MDGoal-Directed Fluid Optimization Based on Respiratory Variations in the Pulse Oximeter Plethysmographic Wave form during Non Cardiac Surgery

Synopsis: To test the hypothesis that monitoring the respiratory variations via the pulse oximeter to guide volume expansion has potential to decrease postoperative morbidity and length of stay in the hospital in patients undergoing routine, moderate-risk elective surgery.

Cannesson, MDCurrent Practice for Hemodynamic Management in Patients Undergoing High Risk Surgery

Synopsis: To assess current hemodynamic management practices in patients undergoing high risk surgery.

Kain, MDParent/Healthcare Provider Behaviors and Child’s Postoperative Pain”

Synopsis: To find out which behaviors impact a child’s postoperative (after surgery) pain and anxiety while in the postoperative recovery area and at home. Studies have shown that adults’ behaviors can impact a child’s pain when children get immunizations. We think that the same thing happens while in the postoperative recovery area and at home. This study will find out which behaviors impact a child’s pain while in the postoperative recovery area and at home.

Kain, MDA Tailored Internet-Based Preparation Program for Pediatric Perioperative Anxiety and Pain

Synopsis: To gather feedback on a new internet based program (WebTIPS) to prepare parents and children for children’s outpatient surgery.

Kain, MDParent/Health Care Provider Behaviors and Child’s Anxiety

Synopsis: To analyze the influence of preoperative behavioral interactions between children, parents and health care providers on children’s anxiety before surgery.

Kain, MDParental Perception and Response to Children's Pain at Home

Synopsis: To find out what parents think about giving pain medication to children, and how parent’s respond to their child’s pain at home. We are also looking at how parents know when their child has pain (how does the child express pain), and if there is any difference based on culture.

Kain, MDThe Relationship between Culture, Socio-Economic Status, and Preoperative Anxiety in Children

Synopsis: To look at the relationship between cultural and socio-economical variables and preoperative anxiety in children before surgery. We are also looking at how gender and temperament relate to anxiety before surgery. Other research studies have shown that culture can affect the experience of pain in adults, but we don’t know how culture may affect pain and anxiety in children and their parents. It is important to understand different variables that may increase or decrease children’s anxiety before surgery because anxiety can affect the way a child recovers after surgery.

Kain, MDThe transition from Acute to Chronic Postoperative Pain in the Pediatric Patient

Synopsis: The purpose of this study is to describe the incidence of persistent postsurgical pain in children up to one year following surgery and to identify factors that may be related to the development of persistent postsurgical pain, including age, gender, and type of surgery.

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